Tuesday, March 14, 2017
Week 10 EOC: The Promoter
A promoter is someone who starts off with an idea and then shows it off to people. "When an individual has an idea for a new business venture, he or she may set about interesting others in the venture and persuade them to contribute capital to a company to be incorporate for the purpose of carrying on the venture." https://www.lawteacher.net/free-law-essays/business-law/role-of-promoters-in-company-establishment-business-law-essay.php It is someone who will publicize and promote upcoming local or national live events and concerts. He or she will also organize the events, book the band or bands, and advertise in a way to bring in as many people as possible, which in turn, will bring in profits. https://www.sokanu.com/careers/music-promoter/ The purpose of the promoter is to bind transcription factors that control the initiation of transcription.The promoter region can be short or quite long; the longer the promoter is, the more available space for proteins to bind.To initiate transcription, a transcription factor (TFIID) binds to the TATA box, which causes other transcription factors to subsequently bind to the TATA box.Once the transcription initiation complex is assembled, RNA polymerase can bind to its upstream sequence and is then phosphorylated.Phosphorylation of RNA polymerase releases part of the protein from the DNA to activate the transcription initiation complex and places RNA polymerase in the correct orientation to begin transcription.Transcription factors respond to environmental stimuli that cause the proteins to find their binding sites and initiate transcription of the gene that is needed. https://www.boundless.com/biology/textbooks/boundless-biology-textbook/gene-expression-16/eukaryotic-gene-regulation-113/the-promoter-and-the-transcription-machinery-457-11683/
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